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Testosterone and NLRP3

Sex differences in inflammation, redox biology, mitochondria and autoimmunity.
Di Florio DN, Sin J, Coronado MJ, Atwal PS, Fairweather D.
Redox Biol. 2020 Mar 4:101482. doi: 10.1016/j.redox.2020.101482. [Epub ahead of print] Review.

Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl4 induced liver injury mouse model.
Ma X, Zhou Y, Qiao B, Jiang S, Shen Q, Han Y, Liu A, Chen X, Wei L, Zhou L, Zhao J.
Am J Physiol Endocrinol Metab. 2020 Mar 17. doi: 10.1152/ajpendo.00427.2019. [Epub ahead of print]

Activation of the NLRP3 Inflammasome Pathway by Prokineticin 2 in Testicular Macrophages of Uropathogenic Escherichia coli– Induced Orchitis.
Li Y, Su Y, Zhou T, Hu Z, Wei J, Wang W, Liu C, Zhang H, Zhao K.
Front Immunol. 2019 Aug 14;10:1872. doi: 10.3389/fimmu.2019.01872. eCollection 2019.

Diacerein Downregulates NLRP3/Caspase-1/IL-1β and IL-6/STAT3 Pathways of Inflammation and Apoptosis in a Rat Model of Cadmium Testicular Toxicity.
Fouad AA, Abdel-Aziz AM, Hamouda AAH.
Biol Trace Elem Res. 2019 Aug 10. doi: 10.1007/s12011-019-01865-6. [Epub ahead of print]

Adrenomedullin alleviates the pyroptosis of Leydig cells by promoting autophagy via the ROS-AMPK-mTOR axis.
Li MY, Zhu XL, Zhao BX, Shi L, Wang W, Hu W, Qin SL, Chen BH, Zhou PH, Qiu B, Gao Y, Liu BL.
Cell Death Dis. 2019 Jun 20;10(7):489. doi: 10.1038/s41419-019-1728-5.

PM2.5 exposure impairs sperm quality through testicular damage dependent on NALP3 inflammasome and miR-183/96/182 cluster targeting FOXO1 in mouse.
Zhou L, Su X, Li B, Chu C, Sun H, Zhang N, Han B, Li C, Zou B, Niu Y, Zhang R.
Ecotoxicol Environ Saf. 2019 Mar;169:551-563. doi: 10.1016/j.ecoenv.2018.10.108. Epub 2018 Nov 24.

Muckle-Wells syndrome and male hypofertility: a case series.
Tran TA, Koné-Paut I, Marie I, Ninet J, Cuisset L, Meinzer U.
Semin Arthritis Rheum. 2012 Dec;42(3):327-31. doi: 10.1016/j.semarthrit.2012.03.005. Epub 2012 Apr 17.