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Asthma and NLRP3

Targeting NLRP3 Inflammasome Activation in Severe Asthma
Efthymia Theofani, Maria Semitekolou, Ioannis Morianos, Konstantinos Samitas, Georgina Xanthou
J Clin Med. 2019 Oct; 8(10): 1615.  Published online 2019 Oct 4. doi: 10.3390/jcm8101615

Heme oxygenase-1 protects airway epithelium against apoptosis by targeting the proinflammatory NLRP3–RXR axis in asthma
Jiajia Lv, Wen Su, Qianying Yu, Meng Zhang, Caixia Di, Xiaoliang Lin, Min Wu, Zhenwei Xia
J Biol Chem. 2018 Nov 30; 293(48): 18454–18465.  Published online 2018 Oct 17. doi: 10.1074/jbc.RA118.004950

Epithelial PI3K-δ Promotes House Dust Mite-Induced Allergic Asthma in NLRP3 Inflammasome-Dependent and -Independent Manners
So Ri Kim, Hae Jin Park, Kyung Bae Lee, Hee Jung Kim, Jae Seok Jeong, Seong Ho Cho, Yong Chul Lee
Allergy Asthma Immunol Res. 2020 Mar; 12(2): 338–358.  Published online 2020 Jan 7. doi: 10.4168/aair.2020.12.2.338

New Insights into Mechanisms Controlling the NLRP3 Inflammasome and Its Role in Lung Disease
Dominic De Nardo, Christine M. De Nardo, Eicke Latz
Am J Pathol. 2014 Jan; 184(1): 42–54.  doi: 10.1016/j.ajpath.2013.09.007

The Role of NLRP3 Inflammasome in Radiation-Induced Cardiovascular Injury
Shanshan Huang, Jing Che, Qian Chu, Peng Zhang
Front Cell Dev Biol. 2020; 8: 140.  Published online 2020 Mar 12. doi: 10.3389/fcell.2020.00140

Estrogen ameliorates allergic airway inflammation by regulating activation of NLRP3 in mice
Cheng Cheng, Huimei Wu, Muzi Wang, Lixia Wang, Hongyun Zou, Shuai Li, Rongyu Liu
Biosci Rep. 2019 Jan 31; 39(1): BSR20181117.  Prepublished online 2018 Oct 29. Published online 2019 Jan 8. doi: 10.1042/BSR20181117

Nasal DNA methylation is associated with childhood asthma
Xue Zhang, Jocelyn M Biagini Myers, JD Burleson, Ashley Ulm, Kelly S Bryan, Xiaoting Chen, Matthew T Weirauch, Theresa A Baker, Melinda S Butsch Kovacic, Hong Ji
Epigenomics. 2018 May; 10(5): 629–641.  Published online 2018 Apr 25. doi: 10.2217/epi-2017-0127

Vitamin D3 levels and NLRP3 expression in murine models of obese asthma: association with asthmaoutcomes
J-H. Zhang, Y-P. Chen, X. Yang, C-Q. Li
Braz J Med Biol Res. 2018; 51(1): e6841.  Published online 2017 Nov 13. doi: 10.1590/1414-431X20176841

Yupingfeng San Inhibits NLRP3 Inflammasome to Attenuate the Inflammatory Response in AsthmaMice
Xue Liu, Jiawen Shen, Danping Fan, Xuemei Qiu, Qingqing Guo, Kang Zheng, Hui Luo, Jun Shu, Cheng Lu, Ge Zhang, Aiping Lu, Chaoying Ma, Xiaojuan He
Front Pharmacol. 2017; 8: 944.  Published online 2017 Dec 22. doi: 10.3389/fphar.2017.00944

4th Pediatric Allergy and Asthma Meeting (PAAM)
Tolga Yavuz, et, al.
Clin Transl Allergy. 2016; 6(Suppl 1): 1–60.  Published online 2016 Nov 21. doi: 10.1186/s13601-016-0117-8

Correlation Between the NLRP3 Inflammasome and the Prognosis of Patients With LSCC
Yi Xue, Huai-Dong Du, Di Tang, Duo Zhang, Jian Zhou, Chang-Wen Zhai, Cun-Cun Yuan, Chi-Yao Hsueh, Sheng-Jie Li, Yu Heng, Lei Tao, Li-Ming Lu
Front Oncol. 2019; 9: 588.  Published online 2019 Jul 2. doi: 10.3389/fonc.2019.00588

Role of the NLRP3 inflammasome in cancer
Maryam Moossavi, Negin Parsamanesh, Afsane Bahrami, Stephen L. Atkin, Amirhossein Sahebkar
Mol Cancer. 2018; 17: 158.  Published online 2018 Nov 17. doi: 10.1186/s12943-018-0900-3

Tranilast directly targets NLRP3 to treat inflammasome‐driven diseases
Yi Huang, Hua Jiang, Yun Chen, Xiaqiong Wang, Yanqing Yang, Jinhui Tao, Xianming Deng, Gaolin Liang, Huafeng Zhang, Wei Jiang, Rongbin Zhou
EMBO Mol Med. 2018 Apr; 10(4): e8689.  Published online 2018 Mar 12. doi: 10.15252/emmm.201708689

Analysis of NLRP3 in the Development of Allergic Airway Disease in Mice
Irving C. Allen, Corey M. Jania, Justin E. Wilson, Erin M. Tekeppe, Xiaoyang Hua, Willie J. Brickey, Mildred Kwan, Beverly H. Koller, Stephen L. Tilley, Jenny P.-Y. Ting
J Immunol. Author manuscript; available in PMC 2013 Mar 15.
Published in final edited form as: J Immunol. 2012 Mar 15; 188(6): 2884–2893. Published online 2012 Feb 8. doi: 10.4049/jimmunol.1102488

A Novel Insight on Endotyping Heterogeneous Severe Asthma Based on Endoplasmic Reticulum Stress: Beyond the “Type 2/Non-Type 2 Dichotomy”
Jae Seok Jeong, So Ri Kim, Seong Ho Cho, Yong Chul Lee
Int J Mol Sci. 2019 Feb; 20(3): 713.  Published online 2019 Feb 7. doi: 10.3390/ijms20030713