{"id":876,"date":"2020-04-09T17:57:14","date_gmt":"2020-04-09T17:57:14","guid":{"rendered":"https:\/\/areyoucovidmune.com\/covidmune\/?page_id=876"},"modified":"2020-04-10T16:14:59","modified_gmt":"2020-04-10T16:14:59","slug":"nlrp3-and-pterostilbene","status":"publish","type":"page","link":"https:\/\/areyoucovidmune.com\/covidmune\/nlrp3-and-pterostilbene\/","title":{"rendered":"NLRP3 and Pterostilbene"},"content":{"rendered":"

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Pterostilbene and NLRP3<\/u><\/strong><\/h4>\n

Dietary\u00a0<\/span>pterostilbene<\/strong>\u00a0<\/span>supplementation attenuates intestinal damage and immunological<\/g> stress of broiler chickens challenged with lipopolysaccharide.
<\/a>Zhang H, Chen Y, Chen Y, Li Y, Jia P, Ji S, Zhou Y, Wang T.
<\/span>J Anim Sci<\/span>. 2020 Jan 1;98(1). pii: skz373. doi: 10.1093\/jas\/skz373.<\/span><\/p>\n

Pterostilbene<\/strong>\u00a0<\/span>Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1\u03b2-Related\u00a0<\/span>NLRP3<\/strong>\u00a0<\/span>Inflammasome Activation.
<\/a>Wang BJ, Chiu HW, Lee YL, Li CY, Wang YJ, Lee YH.
<\/span>J Clin Med<\/span>. 2018 Nov 27;7(12). pii: E489. doi: 10.3390\/jcm7120489.<\/span><\/p>\n

Pterostilbene<\/strong>\u00a0<\/span>inhibits amyloid-\u03b2-induced neuroinflammation in a microglia cell line by inactivating the\u00a0<\/span>NLRP3<\/strong>\/caspase-1 inflammasome pathway.
<\/a>Li Q, Chen L, Liu X, Li X, Cao Y, Bai Y, Qi F.
<\/span>J Cell Biochem<\/span>. 2018 Aug;119(8):7053-7062. <\/span>doi<\/g>: 10.1002\/jcb.27023. Epub 2018 May 8.<\/span><\/p>\n

Pterostilbene<\/strong>\u00a0<\/span>Decreases Cardiac Oxidative Stress and Inflammation via Activation of AMPK<\/g>\/Nrf2\/HO-1 Pathway in Fructose-Fed Diabetic Rats.
<\/a>Kosuru R, Kandula V, Rai U, Prakash S, Xia Z, Singh S.
<\/span>Cardiovasc Drugs Ther<\/span>. 2018 Apr;32(2):147-163. doi: 10.1007\/s10557-018-6780-3.<\/span><\/p>\n

Pterostilbene<\/strong>\u00a0<\/span>Attenuates Early Brain Injury Following Subarachnoid Hemorrhage via Inhibition of the\u00a0<\/span>NLRP3<\/strong>\u00a0<\/span>Inflammasome and Nox2-Related Oxidative Stress.
<\/a>Liu H, Zhao L, Yue L, Wang B, Li X, Guo H, Ma Y, Yao C, Gao L, Deng J, Li L, Feng D, Qu Y.
<\/span>Mol Neurobiol<\/span>. 2017 Oct;54(8):5928-5940. doi: 10.1007\/s12035-016-0108-8. Epub 2016 Sep 24.<\/span><\/p>\n

Pterostilbene<\/strong>\u00a0<\/span>and allopurinol reduce fructose-induced podocyte oxidative stress and inflammation via microRNA-377.
<\/a>Wang W, Ding XQ, Gu TT, Song L, Li JM, Xue QC, Kong LD.
<\/span>Free Radic Biol Med<\/span>. 2015 Jun;83:214-26. <\/span>doi<\/g>: 10.1016\/j.freeradbiomed.2015.02.029. Epub 2015 Mar 5.<\/span><\/p>\n

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[et_pb_section fb_built=”1″ fullwidth=”on” _builder_version=”3.19.3″ background_image=”https:\/\/areyoucovidmune.com\/covidmune\/wp-content\/uploads\/2019\/11\/shutterstock_112250879.jpg” custom_padding=”0px|0px|0|0px|false|false”][et_pb_fullwidth_header title=”Are You CovidMune?™” text_orientation=”center” _builder_version=”3.19.3″ title_level=”h2″ title_font=”|800|||on|||#e02b20|” title_text_color=”#ffffff” content_font=”|700|||||||” content_text_color=”#000000″ subhead_font=”||||on|||#e02b20|” subhead_text_color=”#ffffff” subhead_font_size=”30px” background_image=”https:\/\/areyoucovidmune.com\/covidmune\/wp-content\/uploads\/2020\/04\/covid-19-dna.jpg” custom_button_one=”on” button_one_text_color=”#ffffff” button_one_border_color=”#e02b20″ button_one_font=”|600|||||||” box_shadow_style_button_one=”preset2″][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.19.3″ custom_padding=”7px|0px|0|0px|false|false”][et_pb_row _builder_version=”3.19.3″][et_pb_column type=”4_4″ _builder_version=”3.19.3″ parallax=”off” parallax_method=”on”][et_pb_text _builder_version=”3.19.3″] Pterostilbene and NLRP3 Dietary\u00a0pterostilbene\u00a0supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide.Zhang H, Chen Y, Chen Y, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":""},"_links":{"self":[{"href":"https:\/\/areyoucovidmune.com\/covidmune\/wp-json\/wp\/v2\/pages\/876"}],"collection":[{"href":"https:\/\/areyoucovidmune.com\/covidmune\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/areyoucovidmune.com\/covidmune\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/areyoucovidmune.com\/covidmune\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/areyoucovidmune.com\/covidmune\/wp-json\/wp\/v2\/comments?post=876"}],"version-history":[{"count":5,"href":"https:\/\/areyoucovidmune.com\/covidmune\/wp-json\/wp\/v2\/pages\/876\/revisions"}],"predecessor-version":[{"id":987,"href":"https:\/\/areyoucovidmune.com\/covidmune\/wp-json\/wp\/v2\/pages\/876\/revisions\/987"}],"wp:attachment":[{"href":"https:\/\/areyoucovidmune.com\/covidmune\/wp-json\/wp\/v2\/media?parent=876"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}